Chicken Bubble Biscuit Bake Casserole

Hearty Chicken and Biscuit Casserole: A Delicious Weeknight Dinner

Looking for a comforting and satisfying meal that the whole family will love? Look no further than this hearty Chicken and Biscuit Casserole. Perfect for a cozy dinner on a chilly evening, this dish combines the rich flavors of chicken, cheese, and biscuits in a way that’s sure to please. Below, we’ve outlined everything you need to create this delicious meal, from ingredients to storage tips.


To make this casserole, you’ll need the following ingredients:

  • 3 cups cooked chicken, shredded
  • 1 (10.5 oz) can of cream of chicken soup
  • 1 cup sour cream
  • 1/2 cup milk
  • 1/2 cup shredded cheddar cheese
  • 1 (12 oz) can refrigerated biscuits, cut into quarters
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • Salt and pepper to taste

For the Topping:

  • 1 cup shredded cheddar cheese
  • 1/4 cup butter, melted
  • 1 teaspoon garlic powder


  1. Preheat your oven to 375°F (190°C) and lightly grease a 9×13 inch baking dish.
  2. In a large bowl, mix the chicken, cream of chicken soup, sour cream, milk, 1/2 cup cheddar cheese, garlic powder, onion powder, salt, and pepper until well combined.
  3. Gently fold in the biscuit quarters until they are evenly coated with the mixture. Then, spread this mixture into the prepared baking dish.
  4. Bake for 25 minutes. Remove the dish from the oven and sprinkle the top with 1 cup of cheddar cheese.
  5. Mix the melted butter with garlic powder and drizzle this over the cheese. Return the dish to the oven and bake for an additional 10-15 minutes, or until the biscuits are golden brown.

Serving Suggestions:

Serve this hearty casserole hot from the oven. It pairs beautifully with a crisp green salad or steamed vegetables to add a fresh contrast to the rich flavors of the dish. For an added touch, you can serve it with a side of cranberry sauce for a hint of sweetness.

Storage and Freshness:

Leftover casserole can be stored in an airtight container in the refrigerator for up to 3 days. To reheat, simply cover with aluminum foil and warm in the oven at 350°F (175°C) until heated through, or microwave individual servings for a quick meal.

Frequently Asked Questions:

  • Can I use homemade biscuits instead of refrigerated? Yes, homemade biscuit dough can be used as a substitute. Just ensure the dough is divided into small pieces to spread evenly throughout the casserole.
  • Can I add vegetables to this casserole? Absolutely! Mixing in vegetables like peas, carrots, or broccoli can add color, texture, and nutrition to your casserole.
  • Can this casserole be made ahead? Yes, you can assemble the casserole, cover it, and refrigerate overnight. When ready to bake, let it sit at room temperature for about 30 minutes before putting it in the oven.

This Chicken and Biscuit Casserole is a hearty, comforting dish that’s perfect for any night of the week. With its easy preparation and delicious flavor, it’s sure to become a family favorite. Give it a try tonight and enjoy the warm, satisfying comfort of a home-cooked meal.

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